Overview
Through innovative research and solid results, SomaGenics has made significant progress in its translation of discovery into products.
Therapeutic Pipeline
| Development Highlights |
| Hepatitis C |
- Lead identification complete with IC50 values to 5 picomolar in relevant models
- Identified chemical modification patterns that provide biostability and abrogate immune stimulation
- Achieved substantial knockdown of HCV target in mouse liver with formulated sshRNA
- IND Q3 2010
|
| Psoriasis |
- Genetic targets identified
- Animal models established
- Delivery proof-of-concept studies underway
|
| HIV |
- Early-stage discovery directed toward host targets in progress
|
Nucleic Acid Detection Technologies
SomaGenics has developed detection technologies that provide significant improvements in sensitivity and selectivity over those of competitors.
| Development Highlights |
| miR-ID |
- Kits are now available upon request.
|
| Lasso™ Probes |
- DNA and RNA target capture and enrichment for selective deep sequencing
- Optimization of structure and manufacture complete
- Technology proof-of-concept complete
- SNP detection capability
- Binding kinetics
- Increased signal-to-noise over current products
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